Holiday Inn Express & Suites St. Louise South I-55

4250 Midamerica Lane, Saint Louis, MO, 63129, US

reserve

View Map

Best value

Enter your dates to view
today's low rates and promotions.

Check Rates

Learn more Guest ReservationsTM is an independent travel network offering over 100,000 hotels worldwide. Learn more Guest ReservationsTM is an independent travel network. Learn more

Rooms & Rates

4

Deluxe King Room

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

6

King Room - Disability Access

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

Standard Room

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

6

King Suite

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

6

2 Queen Stndrd Mobil Acc Tub

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

6

Queen Room with Two Queen Beds

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

6

Queen Room with Two Queen Beds - Disability Access

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

Double or Twin Room

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

5

Standard Double Suite

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

4

Suite

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

4

1 King Suite Mobil Acc Tub Extra Living

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

5

2 Queen 1 Bdrm Suite Extra Living Area

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

5

1 King Stndrd Comm Acc Bath Shower Combo

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

4

1 King Standard Bath Shwr Combo

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

6

2 Queen Standard

With your stay:

  • Free Breakfast

Room amenities, details, and policies

Check Rates

Today’s Low Rate Today’s Low Rate

Room amenities, details, and policies

find available rooms

About Holiday Inn Express & Suites St. Louise South I-55

Featuring free WiFi throughout the property, Holiday Inn Express & Suites - St. Louis South - I-55 is located in Mattese. All rooms in the hotel are fitted with a flat-screen TV, microwave and a desk. Other amenities include a refrigerator and a private bathroom with complimentary toiletries. Saint Louis is 13 mi from the accommodations, while Chesterfield is 17 mi away. The nearest airport is Lambert- St.Louis International Airport, 18 mi from Holiday Inn Express & Suites - St. Louis South - I-55.

Amenities

  • 24 hour front desk
  • Fitness Center
  • Refrigerator
  • Concierge
  • Temperature checks are available to guests
  • Wheelchair Access
  • Swimming Pool - Indoor
  • Babysitting Services
  • Masks are available to guests
  • Swimming Pool - Outdoor
  • Contactless check-in and check-out are available
  • Alarm Clock
  • Free Continental Breakfast
  • Guests are provided with free hand sanitizer
  • Microwave
  • Social distancing measures are in place
  • Tennis Court
  • Full Kitchen
  • Non-Smoking Facility

Frequently Asked Questions

The property is located at 4250 Midamerica Lane in Saint Louis.

Prices vary based on dates and availability. Select the dates of your stay above to find the best price on all available rooms.

Yes, this hotel has an indoor pool as well as an outdoor pool for guests to enjoy, along with other amenities. Please see the hotel description above for more information.

No, this hotel does not have an on-site restaurant. Check out the hotel description and the location map to explore local dining options as well.

Guests at Holiday Inn Express & Suites St. Louise South I-55 can enjoy a free continental breakfast each morning during their stay. Refer to the hotel description above to learn more and see what other dining options are available.

Guests at Holiday Inn Express & Suites St. Louise South I-55 can enjoy wide range of amenities such as:

  • indoor swimming pool
  • outdoor swimming pool
  • fitness center or gym
  • tennis court

Check out the hotel description above to learn more about the amenities available during your stay.

Families can enjoy kid-friendly amenities such as a indoor swimming pool, outdoor swimming pool and babysitting services during their stay. Check out the hotel description above to learn more about the family-friendly amenities available during your stay.

We offer a wide variety of rates on Holiday Inn Express & Suites St. Louise South I-55. Discounted rates are available throughout the year, depending on your travel dates. Search for your dates above and we'll show you our lowest prices.

By logging into our site using the login banner above, you'll receive an instant discount of 5% on your booking today with no limit to how much you can save. Log in, claim your promo code, select your dates and room and apply your code at checkout.

Location

Holiday Inn Express & Suites St. Louise South I-55
4250 Midamerica Lane, Saint Louis, MO, 63129, US

View Map

Popular Hotels Nearby

Days Inn by Wyndham St. Louis/Westport MO

Days Inn by Wyndham St. Louis/Westport MO
Extended Stay America Suites - St. Louis - Westport - Craig Road

Extended Stay America Suites - St. Louis -...
Comfort Inn St. Louis - Westport Event Center

Comfort Inn St. Louis - Westport Event Center
Sonesta ES Suites St. Louis Westport

Sonesta ES Suites St. Louis Westport
Comfort Suites St Louis - Sunset Hills

Comfort Suites St Louis - Sunset Hills
Red Roof Plus+ St Louis - Forest Park/Hampton Ave

Red Roof Plus+ St Louis - Forest Park/Hampton Ave

Logo

We are an independent travel network
offering over 100,000 hotels worldwide

Learn more Learn more

Guest Reservations™ is not owned or sponsored by any particular hotel or chain. The use of any hotel trademarks or information is solely for reference purposes in helping customers identify the travel destinations of their choice. All such property, brand, and company names are the registered trademarks or intellectual property of their respective owners. Click here for more information.